Prescribing antidepressants for depression: time to be dimensional and inclusive.
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- Record sourced from PubMed, PMID 21401994.
- Also identified by DOI 10.3399/bjgp11X548992 and PMC identifier PMC3712503.
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Abstract
The article by Middleton and Moncrieff questions the role of antidepressants in treating depression on both philosophical and practical grounds; namely that depression isn't a brain disease to be treated by a drug and that antidepressants are ineffective except as placebos. We argue that their stance is unhelpful and factually incorrect and that a more dimensional and integrative approach is needed in order to be able to best tailor treatment to individual needs. This involves a personalised assessment of the likely benefits and risks of both psychological and drug approaches when recommending treatment for someone with depression.