Dissociation between the secretion and renal action of endogenous atrial natriuretic peptide in the syndrome of inappropriate antidiuresis.
case_report · Level V
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- Record sourced from PubMed, PMID 2140892.
- Also identified by PMC identifier 2429377.
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Abstract
A patient is described with the syndrome of inappropriate antidiuresis (SIAD) and renal sodium retention secondary to a lymphoma. The basal atrial natriuretic peptide (ANP) level and the ANP response to volume expansion were normal (age adjusted) but the natriuretic effect of ANP was attenuated by an unidentified factor. The case emphasizes the dominance of circulating volume over plasma tonicity in the regulation of ANP secretion.
Medical subject headings
- Atrial Natriuretic Factor
- Inappropriate ADH Syndrome
- Kidney