Moving closer to a prognostic DNA methylation signature in colon cancer.
Level V
Where this comes from
- Record sourced from PubMed, PMID 21411436.
- Also identified by DOI 10.1158/1078-0432.CCR-10-3446.
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Abstract
Although large panels of genes undergoing aberrant CpG island methylation in colorectal cancer have been identified, reliable predictors for clinical management in this tumor type remain elusive. A new DNA methylation signature affecting the extracellular matrix (ECM) pathway has been identified with potential prognostic value in colon cancer.
Medical subject headings
- Colonic Neoplasms
- DNA Methylation