GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21421553.
- Also identified by DOI 10.1093/bioinformatics/btr142 and PMC identifier 3087953.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
GO-Module is a web-accessible synthesis and visualization tool developed for end-user biologists to greatly simplify the interpretation of prioritized Gene Ontology (GO) terms. GO-Module radically reduces the complexity of raw GO results into compact biomodules in two distinct ways, by (i) constructing biomodules from significant GO terms based on hierarchical knowledge, and (ii) refining the GO terms in each biomodule to contain only true positive results. Altogether, the features (biomodules) of GO-Module outputs are better organized and on average four times smaller than the input GO terms list (P = 0.0005, n = 16). http://lussierlab.org/GO-Module.
Medical subject headings
- Genes
- Terminology as Topic