Urine screening for Chlamydia trachomatis during pregnancy.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 21422860.
- Also identified by DOI 10.1097/AOG.0b013e3182107d47.
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Abstract
To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution. A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay. A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]). Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay. II.
Medical subject headings
- Chlamydia Infections
- Chlamydia trachomatis
- Pregnancy Complications, Infectious
- Prenatal Diagnosis