High-resolution Fourier-transform infrared chemical imaging with multiple synchrotron beams.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21423192.
- Also identified by DOI 10.1038/nmeth.1585 and PMC identifier 3877692.
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Abstract
Conventional Fourier-transform infrared (FTIR) microspectroscopic systems are limited by an inevitable trade-off between spatial resolution, acquisition time, signal-to-noise ratio (SNR) and sample coverage. We present an FTIR imaging approach that substantially extends current capabilities by combining multiple synchrotron beams with wide-field detection. This advance allows truly diffraction-limited high-resolution imaging over the entire mid-infrared spectrum with high chemical sensitivity and fast acquisition speed while maintaining high-quality SNR.
Medical subject headings
- Microscopy
- Spectroscopy, Fourier Transform Infrared
- Synchrotrons