Human pluripotent stem cells: decoding the naïve state.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21451122.
- Also identified by DOI 10.1126/scitranslmed.3000996.
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Abstract
Human pluripotent stem cells play a central role in regenerative medicine and tissue engineering. These versatile cells can exist in a range of manipulable states with distinct functionalities, from the late epiblast stage represented by the conventional human embryonic stem cells (hESCs) to the mouse ESC-like naïve state. These functional states must be fully characterized if we are to harness the power of pluripotent stem cells to transform clinical medicine and therapeutics discovery.
Medical subject headings
- Pluripotent Stem Cells