Pancreatic endocrine tumors.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21455203.
- Also identified by DOI 10.1038/modpathol.2010.127.
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Abstract
The endocrine cells of the pancreas and their related cells throughout the gastrointestinal tract give rise to a variety of tumors that pose a diagnostic challenge. There has been progress in understanding their histogenesis, morphology, immunohistochemistry, molecular biology and classifications. This review will focus on nomenclature/terminology, classification, the role of immunohistochemistry, molecular advances, including genetic predisposition, and potential therapeutic targets to define the role of pathology in the application of prognostic and predictive markers for this disease.
Medical subject headings
- Neuroendocrine Tumors
- Pancreatic Neoplasms