Is growth hormone resistance/IGF-1 reduction good for you?
Where this comes from
- Record sourced from PubMed, PMID 21459318.
- Also identified by DOI 10.1016/j.cmet.2011.03.003.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
GH, IGF-1, and insulin are emerging as important and independent mediators of tumor development and aging. Two recent studies report that humans with GH-receptor deficiency are protected from developing cancer through alterations in GH, IGF-1, and insulin signaling, decreasing the susceptibility of cells to DNA damage and abnormal proliferation.