Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others.
review · Level V
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- Record sourced from PubMed, PMID 21460130.
- Also identified by DOI 10.3949/ccjm.78a.10145 and PMC identifier PMC11337355.
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Abstract
Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), statins, tamoxifen (Nolvadex), codeine, and psychotropic drugs. It also discusses the future role of pharmacogenomic testing in medicine.