Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: better than we thought.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 21460318.
- Also identified by DOI 10.1093/cid/cir080 and PMC identifier 3070030.
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Abstract
We used Bayesian latent-class models to generate receiver operating characteristic curves and to revise the cutoff values for an enzyme-linked immunosorbent assay that has been developed previously for melioidosis. The new cutoff was unbiased towards misclassification caused by an imperfect gold standard and resulted in an increase in both sensitivity (from 66.4% to 80.2%) and specificity (82.1% and 95.0%).
Medical subject headings
- Bacteriological Techniques
- Melioidosis