HIV transmission: time for translational studies to bridge the gap.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 21471432.
- Also identified by DOI 10.1126/scitranslmed.3002329 and PMC identifier 3767382.
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Abstract
More than 7000 new HIV infections are documented each day worldwide. In this Perspective, we dissect new results from a large clinical trial showing that genital and plasma HIV-1 RNA loads predict the risk of heterosexual transmission and that genital tract viral RNA load does so independently of plasma viral load. Furthermore, beyond its defined study end points, this well-conducted trial identified new research directions that should be pursued in smaller intensive basic and translational studies.
Medical subject headings
- HIV Infections