Derailing heterotopic ossification and RARing to go.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21475232.
- Also identified by DOI 10.1038/nm0411-420 and PMC identifier 4913781.
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Abstract
Retinoic acid receptors inhibit chondrogenesis, but their ability to block the cartilaginous scaffold of heterotopic endochondral ossification has not been explored. A study in mice shows that agonists of retinoic acid receptor-γ potently inhibit heterotopic endochondral ossification, suggesting therapeutic potential in people with this condition (pages 454–460).
Medical subject headings
- Ossification, Heterotopic
- Receptors, Retinoic Acid