Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis.

De Silva, D A; Manzano, J J F; Chang, H M; Wong, M C · Neurology · 2011

review · Level V

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Abstract

We reviewed the literature on IV stroke thrombolysis for patients with recent myocardial infarction (MI). We searched PubMed and Ovid databases, relevant trials, and guidelines. Only 5 thrombolyzed stroke patients with recent MI were reported to have cardiac tamponade. Pathological studies show MI healing is completed by 7 weeks. The time window from MI as a contraindication for IV stroke thrombolysis may be narrowed from 3 months in current guidelines to 7 weeks.

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