An exciting calcium sensor for smell.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21496639.
- Also identified by DOI 10.1016/j.cell.2011.03.047.
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Abstract
Formation of sensory maps within the olfactory bulb depends on insulin-like growth factor (IGF) signaling. Cao et al. (2011) now show that neuronal IGF secretion is regulated by neural activity through the calcium sensor synaptotagmin-10 and is required in the olfactory bulb for the sensation of smell.