Of timing and surrogates: a way forward for cancer chemoprevention.

Thompson, Patricia A; Gerner, Eugene W · Clin Cancer Res · 2011

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Abstract

Cancer chemoprevention strategies are not widely implemented in clinical practice. Targeting biomarkers in patients with elevated risk of developing cancer by means of short-term administration of certain agents may be a strategy to minimize toxicities while maintaining efficacy in clinical trials that can be completed in years rather than decades.

Medical subject headings