Valproate-induced Fanconi syndrome in a 27-year-old woman.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 21516379.
- Also identified by DOI 10.1007/s11606-011-1708-7 and PMC identifier 3157517.
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Abstract
Valproate-induced Fanconi Syndrome (VFS) is a rare complication of this therapy that has been previously described only in children with epilepsy. We report the first known case of an adult with VFS. Metabolic derangements lead patients to present with fatigue, confusion, weakness, and even bone fractures. Identification and discontinuation of the offending agent is the treatment of choice and helps confirm the diagnosis. This case highlights the importance of surveillance for metabolic derangements among patients on long term therapy with this commonly prescribed medication.
Medical subject headings
- Fanconi Syndrome
- Valproic Acid