Bone regeneration and limb lengthening.

Merloz, P · Osteoporos Int · 2011

review · Level V

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Abstract

Regeneration of bone in the presence of stable fixation and the maintenance of the osteogenic tissue (marrow, endosteum, nutrient artery, and periosteum) required another factor to stimulation of bone regeneration: incremental distraction produces bone of both endosteal and periosteal origin. The soft tissues undergo to same growth phenomenon. The mechanism of ossification occurs without intermediate fibrocartilage.

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