Translational control by the eukaryotic ribosome.
basic_science · Level V
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- Record sourced from PubMed, PMID 21529706.
- Also identified by DOI 10.1016/j.cell.2011.04.006.
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Abstract
The ribosome plays a universally conserved role in catalyzing protein synthesis. Kondrashov et al. (2011) now provide evidence that the loss of function of ribosomal protein L38 in mice leads to a selective reduction in the translation of Hox mRNAs, thus suggesting that ribosomal proteins play a critical role during embryonic development.