A potential link between dorsomedial hypothalamic nucleus NPY and energy balance.
basic_science · Level V
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- Record sourced from PubMed, PMID 21531331.
- Also identified by DOI 10.1016/j.cmet.2011.04.006 and PMC identifier 3098526.
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Abstract
The function of dorsomedial hypothalamic neuropeptide Y (NPY) in energy balance has largely been restricted to lactation-induced hyperphagia. In this issue, Chao et al. (2011) expand this role to include inhibition of both brown fat thermogenesis and conversion of white-to-brown adipocytes in a white fat depot, resulting in reduced energy expenditure.