The tragedy of translation: the case of "first use" in human embryonic stem cell research.

Solbakk, Jan Helge; Zoloth, Laurie · Cell Stem Cell · 2011

editorial · Level V

Where this comes from

Abstract

Who should go first in phase-I human trials when neither risks nor benefits can be estimated? By assessing concerns raised by Bretzner et al. (2011), we highlight a tragic dimension underlying all such trials. We discuss strategies to avoid the pitfalls of ethical hubris by promoting fidelity and trust.

Medical subject headings