Acute HIV-1 Infection.

Cohen, Myron S; Shaw, George M; McMichael, Andrew J; Haynes, Barton F · N Engl J Med · 2011

review · Level V

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Abstract

In 2009, the United Nations Estimated that 33.2 Million People worldwide were living with human immunodeficiency virus type 1 (HIV-1) infection and that 2.6 million people had been newly infected. The need for effective HIV-1 prevention has never been greater. In this review, we address recent critical advances in our understanding of HIV-1 transmission and acute HIV-1 infection. Fourth-generation HIV-1 testing, now available worldwide,<sup>,</sup> will allow the diagnosis of infection in many patients and may lead to new treatments and opportunities for prevention.

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