Pharmacokinetics of levetiracetam in neonates with seizures.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 21592494.
- Also identified by DOI 10.1016/j.jpeds.2011.03.057 and PMC identifier 3789844.
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Abstract
The pharmacokinetics of levetiracetam were determined prospectively in 18 neonates with seizures. Neonates were found to have lower clearance, higher volume of distribution, and a longer half-life as compared with older children and adults. Mild somnolence was the only adverse effect.
Medical subject headings
- Anticonvulsants
- Piracetam
- Seizures