Small RNAs loom large during reprogramming.
editorial · Level V
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- Record sourced from PubMed, PMID 21624799.
- Also identified by DOI 10.1016/j.stem.2011.05.009 and PMC identifier 3612285.
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Abstract
In two independent Cell Stem Cell reports, the Morrisey and Mori groups show that human and mouse somatic cells can be reprogrammed to produce induced pluripotent stem cells by expressing microRNAs, completely eliminating the need for ectopic protein expression (Anokye-Danso et al., 2011; Miyoshi et al., 2011).