An update on wound healing and the nervous system.

Abstract

Impaired wound healing is a significant clinical, economic, and social problem. There is a growing body of research over the past several decades that supports the importance of neuropeptides and neurotransmitters in wound healing, particularly in diabetic patients. The purpose of this article is to review current translational research that supports the role of the nervous system in normal wound physiology and the current state of clinical application.