Meningoencephalitis and peripheral neuropathy complicating adult Still's disease.

Abstract

We describe a patient with adult onset Still's disease (AOSD) who developed meningoencephalitis, sensorimotor peripheral neuropathy and uveitis during the course of disease. An abnormal cerebrospinal fluid and changes on nerve conduction studies substantiated the diagnoses of these unusual complications. The meningoencephalopathy improved before corticosteriod treatment, and the peripheral neuropathy and other features of AOSD have responded to corticosteroids. Our case illustrates the rare occurrence of both central and peripheral neurological involvement in AOSD.