Reactions in double emulsions by flow-controlled coalescence of encapsulated drops.

Chen, Haosheng; Zhao, Yuanjin; Li, Jiang; Guo, Ming; Wan, Jiandi; Weitz, David A; Stone, Howard A · Lab Chip · 2011

basic_science · Level V

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Abstract

We demonstrate a microfluidic method to first generate double emulsion droplets containing two different inner drops, and to then control the internal coalescence of the encapsulated drops. The advantages of the core-coalescence method are illustrated by fabricating high viscosity particles and by demonstrating the dissolution of cell membranes.