Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction.
case_report · Level V
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Abstract
Epstein-Barr virus DNA was detected by polymerase chain reaction in a paraffin-embedded block of an undifferentiated lymphoepithelial gastric carcinoma but was absent in a poorly differentiated gastric adenocarcinoma which also had pronounced lymphoid stroma. This is the first report, to our knowledge, of a lymphoepithelial carcinoma of the stomach. The association with Epstein-Barr virus and the distinctive histologic appearance justify the separate classification of undifferentiated lymphoepithelial carcinomas of the stomach similar to those of the nasopharynx from adenocarcinomas with lymphoid stroma.
Medical subject headings
- Carcinoma, Squamous Cell
- DNA, Viral
- Herpesvirus 4, Human
- Stomach Neoplasms