Fine tuning our cellular factories: sirtuins in mitochondrial biology.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21641544.
- Also identified by DOI 10.1016/j.cmet.2011.05.004 and PMC identifier 3111451.
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Abstract
Sirtuins have emerged in recent years as critical regulators of metabolism, influencing numerous facets of energy and nutrient homeostasis. Here, we review recent advances on the role of this fascinating family of mammalian proteins and their well-orchestrated function in modulating mitochondrial activity.
Medical subject headings
- Mitochondria
- Sirtuins