Beyond 5-fluorouracil: the emerging role of newer chemotherapeutics and targeted agents with radiation therapy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21645865.
- Also identified by DOI 10.1016/j.semradonc.2011.02.006.
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Abstract
The management of rectal cancer has undergone significant evolution with advances in surgery, radiation therapy, and chemotherapy. These advances have translated into improved rates of local control, survival, and quality of life. More recently, the integration of newer chemotherapeutic and targeted agents in patients with advanced colorectal cancer have led to further improvements in disease-free and overall survival. These agents are now being studied with radiation therapy in the neoadjuvant therapy of rectal cancer.
Medical subject headings
- Antineoplastic Agents
- Antineoplastic Combined Chemotherapy Protocols
- ErbB Receptors
- Fluorouracil
- Neoadjuvant Therapy
- Rectal Neoplasms
- Vascular Endothelial Growth Factor A