Concise review: challenging the pluripotency of human testis-derived ESC-like cells.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21648019.
- Also identified by DOI 10.1002/stem.669.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Several research groups have claimed to have successfully generated pluripotent or multipotent cells from human testis. However, the pluripotent character of those cells with respect to gene expression profile and ability to generate teratomas has been called into question. Here, we critically review these reports and provide insight to guide future studies on the derivation of human pluripotent cells from testicular tissue.
Medical subject headings
- Embryonic Stem Cells
- Pluripotent Stem Cells
- Testis