Restless legs syndrome and nocturnal myoclonus: initial clinical manifestation of familial amyloid polyneuropathy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 2166139.
- Also identified by PMC identifier 1014216.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Restless legs syndrome was the first isolated clinical manifestation in four siblings of a family with familial amyloid polyneuropathy. Clinical and electrophysiological evidence of peripheral neuropathy appeared after a variable time interval. Polysomnography showed abnormal sleep patterns and nocturnal myoclonus in all patients. The restless legs syndrome responded favourably to clonazepam.
Medical subject headings
- Amyloid
- Amyloidosis
- Genetic Markers
- Myoclonus
- Peripheral Nervous System Diseases
- Prealbumin
- Restless Legs Syndrome