Amniotic membranes in the treatment of necrotizing fasciitis complicating vulvar herpes virus infection.

Rothman, P A; Wiskind, A K; Dudley, A G · Obstet Gynecol · 1990

case_report · Level V

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Abstract

Necrotizing fasciitis of the vulva developed in an immunocompromised patient with chronic myelogenous leukemia, apparently from secondarily infected herpes simplex lesions. In addition to surgical debridements and broad-spectrum intravenous antibiotic therapy, the wound was treated using specially prepared amniotic membranes as a wound dressing. The patient died on hospital day 65 because of complications of her immunocompromised state, with autopsy findings of disseminated cytomegalovirus. However, use of amniotic membranes as a wound dressing appeared to be beneficial.

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