The human brain in a dish: the promise of iPSC-derived neurons.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21663789.
- Also identified by DOI 10.1016/j.cell.2011.05.034 and PMC identifier 3691069.
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Abstract
Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic and psychiatric diseases. Recent work begins to tap this potential and also highlights challenges that must be overcome to be fully realized.
Medical subject headings
- Brain
- Induced Pluripotent Stem Cells
- Neurons