Allergic diseases, gene-environment interactions.

Renz, H; Conrad, M; Brand, S; Teich, R; Garn, H; Pfefferle, P I · Allergy · 2011

Level V

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Abstract

Allergic asthma develops in part from dysregulation of the innate and adaptive immune functions, particularly an imbalance in the Th2-driven adaptive immune response. This dysregulation is the result of complex interactions between genes and environment. These interactions occur both pre- and postnatally, providing opportunities for early interventions in immunological programming.

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