Immunohistochemical study of IOT-10 natural killer cells in brain metastases.
basic_science · Level V
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Abstract
The presence of NK-cells in a series of 40 metastatic brain tumours has been studied by means of the monoclonal antibody IOT-10. There appeared IOT-10 NK-cells in all tumours studied, but in most cases these cells represented less than 10% of the tumour infiltrating lymphocytes (TIL). In the present series, the obtained data suggest that the number of NK-cells in brain metastases can be influenced by other factors than the mere quantity of TIL.
Medical subject headings
- Brain Neoplasms
- Killer Cells, Natural