Detection of multiple disease indicators by an autonomous biomolecular computer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21671655.
- Also identified by DOI 10.1021/nl2015872.
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Abstract
The promise of biomolecular computers is their ability to interact with naturally occurring biomolecules, enabling in the future the development of context-dependent programmable drugs. Here we show a context-sensing mechanism of a biomolecular automaton that can simultaneously sense different types of molecules, allowing future integration of biomedical knowledge on a broad range of molecular disease symptoms in the decision of a biomolecular computer to release a drug molecule.
Medical subject headings
- Computational Biology
- Computer Simulation
- DNA
- DNA-Binding Proteins
- RNA
- Software