SGK3: a novel regulator of renal phosphate transport?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21673735.
- Also identified by DOI 10.1038/ki.2011.60.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Phosphate is a key constituent of several important molecules, and hyperphospatemia has been associated with increased cardiovascular mortality. The kidney plays a crucial role in phosphate metabolism, as it is able to modulate phosphate excretion. Serum- and glucocorticoid-inducible kinase 3 (SGK3) has been shown to regulate a wide variety of transport systems. Bhandaru et al. suggest that SGK3 may have a significant role in the regulation of renal tubular phosphate transport.
Medical subject headings
- Bone Density
- Hypophosphatemia, Familial
- Protein Serine-Threonine Kinases