Weight-based loading of vancomycin in patients on hemodialysis.

Brown, Merideth; Polisetty, Radhika; Gracely, Edward J; Cuhaci, Bulent; Schlecht, Hans P · Clin Infect Dis · 2011

prospective_cohort · Level II

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Abstract

We evaluated weight-based loading doses of vancomycin and resulting initial prehemodialysis concentrations. Modeling demonstrated modest correlation between dose administered, age, and initial concentration achieved. Actual body weight-based loading of vancomycin predictably achieves therapeutic initial concentrations in patients who receive hemodialysis.

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