Pro-senescence therapy for cancer treatment.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21701512.
- Also identified by DOI 10.1038/nrc3057.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Abundant evidence points to a crucial physiological role for cellular senescence in combating tumorigenesis. Thus, the engagement of senescence may represent a key component for therapeutic intervention in the eradication of cancer. In this Opinion article, we focus on concepts that are relevant to a pro-senescence approach to therapy and we propose potential therapeutic strategies that aim to enhance the pro-senescence response in tumours.
Medical subject headings
- Cellular Senescence
- Neoplasms