A pharmacological approach to first aid treatment for snakebite.

Saul, Megan E; Thomas, Paul A; Dosen, Peter J; Isbister, Geoffrey K; O'Leary, Margaret A; Whyte, Ian M; McFadden, Sally A; van Helden, Dirk F · Nat Med · 2011

basic_science · Level V

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Abstract

Snake venom toxins first transit the lymphatic system before entering the bloodstream. Ointment containing a nitric oxide donor, which impedes the intrinsic lymphatic pump, prolonged lymph transit time in rats and humans and also increased rat survival time after injection of venom. This pharmacological approach should give snakebite victims more time to obtain medical care and antivenom treatment.

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