Inflaming hypothalamic neurons raises blood pressure.
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- Record sourced from PubMed, PMID 21723497.
- Also identified by DOI 10.1016/j.cmet.2011.06.006 and PMC identifier 3131053.
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Abstract
Obesity and hypertension are strongly associated, and neural dysfunction has been implicated in both. The hypothalamus integrates signals regulating blood pressure and energy homeostasis. A recent paper in Nature Medicine (Purkayastha et al., 2011) suggests that obesity and hypertension are caused by inflammation in distinct hypothalamic neuronal populations.