Pluripotency without Max.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21726827.
- Also identified by DOI 10.1016/j.stem.2011.06.010.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Myc/Max complexes are thought to be essential for maintaining pluripotency and self-renewal of embryonic stem cells (ESCs). In this issue of Cell Stem Cell, Hishida et al. (2011) provide genetic evidence that this requirement can be bypassed in well-defined culture conditions.