Development of newborn and infant vaccines.
Where this comes from
- Record sourced from PubMed, PMID 21734174.
- Also identified by DOI 10.1126/scitranslmed.3001880 and PMC identifier 4108897.
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Abstract
Vaccines for early-life immunization are a crucial biomedical intervention to reduce global morbidity and mortality, yet their developmental path has been largely ad hoc, empiric, and inconsistent. Immune responses of human newborns and infants are distinct and cannot be predicted from those of human adults or animal models. Therefore, understanding and modeling age-specific human immune responses will be vital to the rational design and development of safe and effective vaccines for newborns and infants.
Medical subject headings
- Immune System
- Infant, Newborn
- Vaccines