Acute fall in glomerular filtration rate with renin-angiotensin system inhibition: a biomeasure of therapeutic success?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21760601.
- Also identified by DOI 10.1038/ki.2011.132.
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Abstract
Glomerular filtration rate (GFR) acutely declines with the introduction of renin-angiotensin system inhibition. This response is functional, not anatomical, and varies with volume status. The reduction in GFR with renin-angiotensin system inhibition may serve as a biomeasure of future therapeutic benefit.
Medical subject headings
- Angiotensin II Type 1 Receptor Blockers
- Antihypertensive Agents
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Glomerular Filtration Rate
- Hypertension
- Kidney
- Losartan