Bayesian community-wide culture-independent microbial source tracking.
Where this comes from
- Record sourced from PubMed, PMID 21765408.
- Also identified by DOI 10.1038/nmeth.1650 and PMC identifier 3791591.
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Abstract
Contamination is a critical issue in high-throughput metagenomic studies, yet progress toward a comprehensive solution has been limited. We present SourceTracker, a Bayesian approach to estimate the proportion of contaminants in a given community that come from possible source environments. We applied SourceTracker to microbial surveys from neonatal intensive care units (NICUs), offices and molecular biology laboratories, and provide a database of known contaminants for future testing.
Medical subject headings
- Bayes Theorem
- Disease Reservoirs
- Environmental Monitoring