A microchip-based model wound with multiple types of cells.

Xie, Yunyan; Zhang, Wei; Wang, Liming; Sun, Kang; Sun, Yi; Jiang, Xingyu · Lab Chip · 2011

basic_science · Level V

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Abstract

Collective migration is critical to many physiological processes, but few methods allow for studying this behavior with precisely controlled cell-cell interaction. Here we report the development of a microchip based on co-culture of different types of cells and selective injury, and explore the dynamics of epithelial collective migration triggered by a real cell group.

Medical subject headings