Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders.

Rosen, Rachel; Johnston, Nikki; Hart, Kristen; Khatwa, Umakanth; Katz, Eliot; Nurko, Samuel · J Pediatr · 2011

prospective_cohort · Level II

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Abstract

The aim of the study was to determine if children with chronic cough or wheezing and with more full-column, nonacid reflux have a higher likelihood of a positive bronchoalveolar lavage fluid culture. In a prospective study of 46 children with cough who were undergoing endoscopy, multichannel intraluminal impedance testing, and bronchoscopy, we found that patients who had a positive culture had significantly more full-column, nonacid gastroesophageal reflux than those who had a negative culture.

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