Nuclear pore structure: warming up the core.

Harel, Amnon; Gruenbaum, Yosef · Cell · 2011

basic_science · Level V

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Abstract

Structural determination of the nuclear pore complex has been limited by the complexity and size of this cellular megalith. By taking advantage of exceptionally stable nucleoporins from the thermophilic fungus Chaetomium thermophilum, Amlacher et al. (2011) provide new insight into a core element of the nuclear pore scaffold.