Radiologic aspects of immune-related tumor response criteria and patterns of immune-related adverse events in patients undergoing ipilimumab therapy.

O'Regan, Kevin N; Jagannathan, Jyothipriya P; Ramaiya, Nikhil; Hodi, F Stephen · AJR Am J Roentgenol · 2011

case_series · Level IV

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Abstract

The objective of this article is to illustrate examples of radiologic immune-related response criteria and toxicity in patients with advanced melanoma treated with the immunotherapeutic agent ipilimumab. Novel immune-related tumor response criteria should be applied to patients undergoing therapy with ipilimumab for advanced melanoma. Ipilimumab also produces a spectrum of immune-related adverse effects that can be recognized radiologically.

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